Wth Sarah Hunter still sidelined by injury, and Emily Scarratt dropping to the bench, Mclean is handed the role again, having led England over a number of years including to the World Cup win in France in 2014.
She is one of numerous changes in the side who won in Grenoble, among them the move of Claudia MacDonald to the wing, a role she has occupied for England twice before, both in 2019. Jess Breach picked up an injury in last weekend’s victory so she misses out out side.
The game is live on BBC 2 again with a midday kick-off, following a positive debut on the channel last weekend where a peak of 800,000 viewers turned in.
Centre Lagi Tuima makes her first appearance since June 2019, replacing Scarratt while Harriet-Millar Mills starts at blind-side flanker.
France have brought back Safi N’Diaye after her side lost out 10-33 last weekend.
The Montpellier player, the most experienced in the squad, will celebrate her 76th selection for France in the game and she is one of four changes.
The other three changes come in the backs. Jade Ulutule and Elise Pignot are the new centre partnership, while Cyrielle Banet, is named on the wing.
Jessy Trémouliere is back but she is only named on the bench. Shannon Izar had a good outing last weekend at 15 so she gets another go.
England Head coach Simon Middleton said: “Playing three physical matches against top opposition back-to-back is very attritional and understandably can take its toll.
“When I asked Katy if she’d captain the side, I honestly didn’t know it would fall on such an occasion and knowing her as I have come to I’m pretty sure she didn’t either. What I do know is that even after winning the World Cup as captain in 2014, the smile on her face when I asked her to captain the side said everything you need to know about one of England’s greatest-ever players.
“Last week we had to see how we coped without the experience of Katy at fly half, this week is an opportunity to see how we fare without Emily Scarratt in the starting XV. Lagi was out for a long time, she’s now back playing for Harlequins and in training with us and we’re looking forward to seeing what she can do on the Twickenham stage.
“Harriet Millar-Mills thoroughly deserves her start. She’s been exceptional for us on and off the field."
England Ellie Kildunne, Claudia MacDonald, Lagi Tuima, Zoe Harrison, Abby Dow, Katy Daley-Mclean, Leanne Riley, Vickii Cornborough, Lark Davies, Shaunagh Brown, Abbie Ward, Morwenna Talling, Harriet Millar-Mills, Alex Matthews, Poppy Cleall
Replacements: Amy Cokayne, Ellena Perry, Laura Keates, Sarah Beckett, Marlie Packer, Natasha Hunt, Helena Rowland, Emily Scarratt
France: Shannon Izar, Coralie Bertrand, Elise Pignot, Jade Ulutule, Cyrielle Banet, Caroline Drouin, Laure Sansus; Annaëlle Deshave, Agathe Sochat, Rose Bernadou, Céline Ferer, Safi N'Diaye, Marjorie Mayans, Gaëlle Hermet (c), Emeline Gros
Replacements: Laure Touye, Maylis Traore, Clara Joyeux, Coumba Diallo, Romane Menager, Pauline Bourdon, Morgane Peyronnet, Jessy Trémouliere